Dave is responsible for the preclinical discovery platform with which WuXi AppTec supports its collaborators in Europe and Israel. With a background in medicinal chemistry, Dave joined WuXi AppTec 7 years ago, after working in biotech (VP Research, Xention), founding NCE Discovery (now Domainex), and supporting an integrated biomedical research group at University College London. Dave started his career at the Wellcome Foundation and received his Ph.D in Chemistry from Imperial College, London.
Past, Present, and Future of Ultra-Large Library Exploration
Christian received his Ph.D. from the University of Bonn for his work on the FlexS system for the automated superposition of small molecules. In 1999, he began his industry carrier as Senior Research Scientist at the biotech company CombiChem in Palo Alto CA. Later this biotech became part of DuPont Pharmaceuticals and moved to San Francisco. In 2001 he returned to Germany and co-founded BioSolveIT. Dr. Lemmen’s vision is to revolutionize the drug-discovery process by empowering every chemist with the best algorithms wrapped inside the most intuitive user-interfaces.
Virtual Screening in the Schrödinger Platform - Generating Novel Hits from Searching Large Chemical Spaces
Thomas Steinbrecher studied Chemistry at the University of Freiburg in Germany and earned a diploma with distinction in Physical Chemistry. He completed a Ph.D. thesis on “Computer Simulations of Protein-Ligand Interactions” in 2005. He joined the developer team of the Amber MD package as a Postdoc at the Scripps Research Institute in San Diego and Rutgers University in New Jersey. The work focus was on efficient free energy calculation methods and QM/MM simulations of charge transfer. After returning to Germany in 2008, Thomas established a junior research group at the Karlsruhe Institute of Technology, working on fast electron transfer phenomena in DNA and proteins. He joined Schrodinger in 2013 where he was responsible for the large scale application of free energy calculation methods in pharmaceutical drug design. Since 2017, he heads the Applications Science Department for Europe and supports customers in employing Schrödinger’s Drug Discovery Technology Platform for their research.
Title to be announced
Dr Binglin WANG
WUXI APPTEC (WUHAN) CO., LTD, Wuhan, Hubei, China
Harnessing the Power of Exploring Large Chemical Space for Novel Hit Finding
Li Xing is Executive Director at WuXi AppTec, leading the computational chemistry function responsible for discovery research of broad biological interventions as well as modern technology advancement. Prior to joining WuXi, she spent more than fifteen years at Pfizer Global Research, co-inventing pharmacotherapies of various disease indications and advancing multiple compounds to human clinical development. A passionate drug hunter, Dr. Xing specializes in computer aided drug discovery, with a focus on applying computational technologies to solve real-time problems in pharmaceutical research. She has published more than one hundred peer-reviewed journal articles and international patents. She received her Ph.D. in polymer science from University of Akron, and double bachelor degrees in solid state physics and computer technology from Tsinghua University.